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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5591c7b65b731b505aea4acfb6e4a44b7251e063b65cb9b02b3423e547660ba0' 
  AND token = 'jpNktGD6SZc3Ef02JuEpHT7MwJ41hHj0G8bZL8Z+/9c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}