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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c225b2e122c5765e0478650e766bb48fe6b18b9657ea2c3be1b7d41fb458bfb2' 
  AND token = 'ABbUjtM5jYuRJ/XE+V0G/DWi2yhTsO9HRKKzfSdjkEM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}