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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd154b2bef0c59314f03076625b41807ae0eb64bedefffc5edf3c3bd8a833e1c8' 
  AND token = 'W2If9NnzFUMORNK6gTDmpk8CESBpcH7LFXSnLb4f5ho=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}