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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a46f8437d131ea10a5448203df070484f45544ad7bda575794296f1dac6976b' 
  AND token = 'Y/dKe6pyAeFN2jUPCtTO5HYIvev2persQdKFSgKX08Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}