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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2f1586048d65ec618652813f99a06ce0ebb11abef6d501d458d22fb043f4fc4' 
  AND token = 'pyzmP7C7Nxad1f1wP/IJ7vgciQh3JZbDq5ljgWUkfiI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}