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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44ff5f6f9c2da80cb4865c2aaf33fcf5bacca6974209b8698b6e5d7215c0ee36' 
  AND token = 'pA+D0sv0Fpyizolv2Tg/nCV5hEwiN9uhmATwMl8t9GU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}