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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '189e28426538f9d3ebed1e010e2f48e008c65ee1bc244e0117cd3558163d8a16' 
  AND token = 'XCAR/GovxeRpsYYBI2qb+d/lqxZBGTGadwraMcNeJRU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}