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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3eedd3452fe78cc9cbf8bc3da87558e5af1406342d721df7d9d4cbca20b61cd' 
  AND token = 'e4fQJZcoi+woiKZhy2EIx53nzExJ5gp1GZU7PgX2fwg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}