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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '293a8d23ab111c371af16fc9aa77d4be564e106b45fbc7777eee0a493807197d' 
  AND token = '1+V7bxQjAO3mCemhKI171zgvEgP9MZO3D3F3W8EIUHY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}