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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67c31366d0e6abbc4e6c1fcaa97bb6f8a9e396979654bd359ee8ac5cbb73152b' 
  AND token = '9NijbnTy7fA0C1W+jCG3eLGaEgMN1+ngS+tUlzV0KNo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}