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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1b01e1acc301ff405b924d7955c4cb4ddb6baf4cd13f5efb906ef75c2392cd4' 
  AND token = 'FRPGueH76GMUpRimt8jeCUge4ubN20JlPxf7IO5i5E0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}