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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b6ed8416f752e35817825acb48cedd5b2e57d01098caf34a318c0083f4269de' 
  AND token = 's32xqfcdV7luXv/htPQWKCDTfPRn0yPC3QcSOnat71g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}