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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '58715b9ebf871fc80c599a257f181fec9c7c6a6fd9dd6fbbc515675781ba8e30' 
  AND token = '2/sM0KHc1/9SST+QeLNwUj/cPi17WDtRXpLWUBuUE1k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}