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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '02fa25a034ea2e5141dc293d016e4ddf48519f23579bfe3fa00234d9b2977ac0' 
  AND token = '432PGEMctNgTzlGJf2fmclSyhkpsrbQNnru4EmeLfp4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}