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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a48049169cf90e3bd977f3035c8851deeeb1e3f519d7ed0a4c296d7d8e090a20' 
  AND token = '5Ga59rtvZntFRn9UE5GjtXFlBLJD+HSQz2CHF1ueVWk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}