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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3d910199880009acdc406f64531d129058d411d563343dead9353b079603cc9' 
  AND token = 'trh1PxVWp95O+9Nf1LcoO+wDMCnpeqva9Ile8W1IhDE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}