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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5173c5f77b8157a8b635c0b1c58639bb8b68ac1d6c257c62169c7e5675f74327' 
  AND token = 'IHcKpbxDjKBAeZ9Pe9x+Yj3dWST3/ocay/IXh4uxI64=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}