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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d681e937a0c3a50a0253d22dc914007b2ac1c8065496fb3b288fd5756c79df1' 
  AND token = 'aPO55ye1WrH3eMily7yXYNFXZwasB2icco7+RPhgtVU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}