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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8fc9e4c44a8666ea6fce5ceeb324f544928fc35537be2a124c8a9a43225b3649' 
  AND token = 'nKbtiJXy7WcsuavOopmXovzg2/OWm0WBSho5y3F5FkE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}