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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b544cc53e980ef720a666ae89073b8b8fae31b01e6d81dc548bc8c9d9053418c' 
  AND token = 'wnVGe22fKl1jowq7xyMA4WbXUYNlkfWgzBwouNJG2UM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}