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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '185d479b3d2398fc6450b81351f12d5504a85911d4797e1a40ba67ec3055229c' 
  AND token = 'd4F2ol/gcILT0DLs94lKNHhUj8jKxoMFUtQcfrLXlWs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}