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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d7e90466ab6c4ff9a3cc5ab631fe8cca4591e7d7e16669c4c7b8753596f1528' 
  AND token = 'qYDUYmP4NKaZ7MUx3Tz9h3uaLj8PRTIsDUm9qdu0E/w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}