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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10698e674461459d42b4b2d2c1014219da71bc96620cf686569ac1cdfbb4d99a' 
  AND token = 'NnN8TcMqDffvXZg9XoRFoDARLNcgue/1NebVUt/sFSI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}