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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3def55b81b5187704344a040a0bd24dece416cb4797ad730df549313ee56804' 
  AND token = '4IGy6Ifcw1B/0sZ5YEdJgws9sp66RgLA0RU/CE2cGzs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}