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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '904594f1f7d7f507eb5e14deaf8c4847e039349ff22ca41be43eb154d387bbb1' 
  AND token = 'fcLmXOGpdx4eRWA+KbWporSaT1bZ9KBrfNCx3BWtalk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}