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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5c56f881f552bf7f8aa63dcc9e025ccf9f7eb682b489464a9bda06e71595e20' 
  AND token = 'z/sBKDpDWWa/6DaYGLI8cfKjcpuqD1H6qlUqMCwpDUI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}