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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c92e9c850d9af7b431212338cef34ce05a566d4b3e64c51a7e678a064101259' 
  AND token = 'Ad4FRHS2b4IiRUbQKW8YYBJQn5rjPaG1TRq9YozWtzw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}