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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0376ccdb09a494c404c48c5d272fddb8cec2f6a8558c05daea0fc7d4a1d9eb6' 
  AND token = 'VZ/P+5+mgI4V666B17MYTOJZ7iZf106chJLjAqARhxU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}