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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '288c70cf1fb432b18a0d362f02916c06e0e170d407252be7117ee5c2c970c146' 
  AND token = 'edT0oJwpKifKj65vz2UpuCa8LED1mjT23vl89/dT3Gg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}