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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1afb2f66715985edbd447c482c97f54b18d24d136e66b4691c5b929b16c63e0' 
  AND token = 'U0mGUISvqK0GcM6LEz34mJcghOWrQbXyOQ2AHWbKdbk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}