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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a776b74fd9a1d2c6e84eed63c55069f507968e8ba4da839b67ff5f0e94202d3' 
  AND token = 'tYXKEo9rE3CLXTUWgRuo1142jyr/N5SZ0TzdKVg8fd4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}