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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59fed5b38200456e4cfb772876ed3c979894bc7c59305c88bd3c2634c52ec856' 
  AND token = 'BwFa9p+AO+kYZHoBizMpNgC99pEixCP6etrvn5etYp4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}