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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'adbc21e91899c22d142311492ea2b3cbbbe5ba2fb9177303e456f3cff78ac317' 
  AND token = '7265RLPvQX5WTzY0hU9bRYVsDvxZwX6eH8F7aF6ZOos=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}