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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b88d3f0921249d58069d180ca31cf8d5578aab787024e46eb49e932d378e44d' 
  AND token = '19iz17Lap+IRnXqRCp5oYIc32U2lxmmpuwybam1MEOk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}