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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a52141b0281ae5d55385a5cc03d70d940317808b641dcd3c3b5fb2cb411faf02' 
  AND token = '3F5QCL2NYua2+Bll/9ZvboFBSbDTAjnF+VtNBpqvbz4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}