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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2e66a9d73d119e543f6102838fee71f770a28199a8af35a8a16a3254e2ce44c' 
  AND token = 'SilS6V/ZEpGLwQ8V1nvocaQKrjwrBhuPwucSpkKyoj0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}