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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52a6cf8e922a51252cf596161caec34e9c60d3d626fb28d23b50b345de8a5224' 
  AND token = 'j8FbqsZ8nrP0rmcr0LM8vE3m7zhZy8DPErCsidLITn0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}