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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af3c7d2ab06d971e04d04edec0e70b7ffadae4f11883aaf600b68c7264af4ce2' 
  AND token = 'TZuYZjO+W8EYrkRG1yIF9KXnAHWe+q3sUc/OSFT6EQ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}