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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5899670bb5d4e72cfd91498a59b3f54108eceb42531dc1b6c9eac395979bf46f' 
  AND token = 'YcjyCbpq/sbp29Sc6UKYt78L+dcS9FaU114IHw7iEyQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}