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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c81194247c3d9577d7125dc49a026a1eafdcb97c9bda8effd97aadd7e86ceefe' 
  AND token = '8uykka9G7IlSs/Zo72NHx1EHW6EozgZwjZebhlfFgiY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}