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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54c01770513f9b16781dfe54bdbc50811053fea1bfacb120567657398306fb54' 
  AND token = 'WiEsEpGpj5xluh1JnWcW+0HfoO3SsVgVqh2Mj2o6DTE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}