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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c20c3bd5c743c073b18db325e99c2ad025978ac3bdf0d8693f6296d2950a72b4' 
  AND token = 'RHT1N2gBX07M9lLmiUDlXG5DBJMvqeTnh3R7UJ4plyg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}