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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d4443271c002142d50a33f89e4a1460074d81c6d1e780b4014dd859d080ffab' 
  AND token = 'VOF9M/tRyBD43zlCEzdXQc9PcmkWNgcaotvAYZCzLUU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}