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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '76feb22b8aff09e92169960f6cce45e5a04e6c1f0889d104127d70d039c4c0dd' 
  AND token = 'jFbR8FGRdFwWsz0+vqnuUn8xvAdjEmHHBrtCVeEMPME=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}