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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9839f680419f1133473a7149f8bf693cfb4ca130e9449f5018503369a58401a6' 
  AND token = 'VJ9r4eZdFNnONNi5aP71ZEA6dZJtZ1dWnCGrZ7MKGEs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}