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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8fce0703d249de9c1e5406b0ba85b9c48775e6f69d079519c527c2c54f15dbb0' 
  AND token = 'BfZr64iuO+qM5MGZtOrOrsgPkeFPymfkx6DyrVKc5aI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}