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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d8d0d832e131745ef98393f456defac5161c1ab6d6ee884bd8f69376b8276b5' 
  AND token = 'EKcQfmO3XWkZzabL9q5k6FboTwYV19tPXJrhwA4FZnM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}