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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c06579aec4acfe23733a0beb93ec9dc39b124bd22ea964a22a0a72398d76919e' 
  AND token = 'zI33Cn4V0/30T8V8RkeNUm8KUKf36dTBs9gUa5axcmc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}