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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff4558cca463fd4c608fa2a9d66dbb1efa10d37a06f2d53427ce7affbd50d472' 
  AND token = 'FP5v+Bgz0BnZMgi2oeurilksPEsVireBup5Fb7ZWrc0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}