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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24bc58ebb8513327a51b1f3fccb84dbe223c6e4777b21c8413f7eeda452aa090' 
  AND token = 'GNhgHWT7Zoe1lBDyDcw9/s2nTCPmLToXvLg+rEpqgBk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}